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In Figure 4 It was observed that, compared to the normal architecture and regular pattern of hepatocytes with active vesicular nuclei in G1 (Normal control), the liver of G2 (MTX) showed central vein dilation and congestion (a in Figure 4B), Focal cell necrosis, hepatocyte nuclei of many cells are dark stained, and small apoptosis was also observed

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J Pediatr 138(Suppl):S46S55 Arbeiter AK, Kranz B, Wingen Bonzel KE, Dohna AM, -Schwake C, Hanssler L, Neudorf U, Hoyer PF, Bscher R (2010) ontinuous venovenous haemodialysis (CVVHD) and continuous peritoneal dialysis (CPD) in the acute management of 21 children with inborn errors of metabolism

The canonical and noncanonical NF-B pathways differ in signaling mechanisms but are responsible for regulating inflammatory responses [17]

Saraiva, C., Paiva, J., Santos, T., Ferreira, L